Medicus Research: Research Experience

Research Experience

Allergy
XXX for the attenuation of nasal provocation with histamine in seasonal allergic rhinitis: A randomized, double-blind, placebo-controlled, 3 day-dosing, cross-over study.

XXX for the attenuation of nasal provocation with histamine in seasonal allergic rhinitis: A dose-finding, randomized, double-blind, placebo-controlled, one month cross-over study.

Arthritis
A Randomized, Multi-center, Double-blind, Single- Dose Study of the Analgesic Properties of XXX and Placebo in Subjects with Pain caused by Mild to Moderate Osteoarthritis of the Knee.

A Phase 2B, Randomized, Double-Blind, Placebo-Controlled Active Comparator, Multicenter Study to Compare 5 Dose Regimens of XXX and XXX versus Placebo, Administered for 6 months in the treatment of Subjects with active Rheumatoid Arthritis.

A 4-Week, Randomized, Double-Blind, Placebo-and Positive-Controlled, Parallel-Group, Multicenter Study of XXX in Subjects with Symptomatic Osteoarthritis of the Knee.
XXX for the Improvement of Function, Quality of Life, and Pain in Patients with Knee Osteoarthritis: A Randomized double-blind placebo controlled study.

Asthma
A randomized, Multicenter, placebo-controlled parallel group study of four months duration per patient to evaluate the safety and efficacy of treatment with xxµg b.i.d. and xx µg b.i.d. XXX, double-blind, and xx µg b.i.d.XXX with additional on-demand XXXl doses, open-label, in adolescent and adult patients with persistent stable asthma.

Bioavailability
Relative Peak Absorption and Steady State Bioavailability of 2 XXX formulations: a Crossover study.
XXX Softgel vs. Powder Bioavailability Study.

Relative Bioavailability of XXX Compared to USP XXX Isolate, XXX National Brand A, and XXX National Brand B.

Relative Bioavailability of XXX brand Selenium, Chromium and Vanadium in a Mineral Product.

Bioavailability of XXX Vitamins and Minerals in healthy volunteers: A pilot study.

Evaluation and Bioavailability of XXX: A Randomized, Double-Blind, Parallel Group Study.

Cardiovascular / Lipids
A multi-component therapy including XXX, XXX, and XXX for the improvement of the cardiovascular risk profile in a moderately at-risk population.

A proprietary herbal combination formula XXX for the reduction of hyperlipidemia in subjects with low to moderate cardiovascular risk: A randomized, double-blind, placebo-controlled, parallel-group trial.

An Open-Label, Controlled Multiple-Dose Randomized Parallel Group Adiponectin / Insulin / Glucose Concentration Response Study in Insulin Resistant Patients.

A Dose Ranging Study to Evaluate the Tolerability of XXX and its Effects on Niacin Induced Acute Flushing in Lipid Clinic Patients and/or Normal Healthy Subjects.

A Soluble Fiber and Plant Sterol-Containing XXX for Lowering Cholesterol: A Randomized, Double-Blind, Placebo Controlled Study.

A Worldwide, Multicenter, Double-Blind, Randomized, Parallel, Placebo-Controlled Study to Evaluate the Lipid-Altering Efficacy, Safety, and Tolerability of XXX in Patients with Primary Hypercholesterolemia or Mixed Hyperlipidemia.

Dermatology
Measuring Acne Outcomes in Real World Experience Trial (The MORE Trial).
Safety and Effectiveness of a Lysine Based Product on the Treatment of Facial and Circumoral Herpes.

Diabetes / Glycemic Index
The Effect of XXX on the Glycemic Index of High Glycemic Test Foods: A 3-way, randomized, single-blind, dose-finding, crossover study.

Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of XXX as Monotherapy in Subjects with Type 2 Diabetes Who Have Inadequate Glycemic Control with Diet and Exercise.

Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of XXX as in Combination with Metformin in Subjects with Type 2 Diabetes Who Have Inadequate Glycemic Control with Diet and Exercise.

A Multicenter, Randomized, Double-Blind Factorial Study of the Co-Administration of XXX and Metformin in Patients with Type 2 Diabetes Mellitus who have inadequate Glycemic control.

A 24-Week Randomized, Double-blind, Double-dummy, Multicenter Study to Compare the Efficacy of Extended Release XXX (xxmg OD) and Immediate-Release XXX (xxmg OD) in Subjects with Type 2 Diabetes Mellitus.

A 24-Week Randomized, Double-blind, Double-dummy, Multicenter Study to Evaluate the Safety, Efficacy, and Tolerability of Modified Release XXX (xxmg OD) and XXX (xxmg BD) in Patients with Type 2 Diabetes Mellitus.

A Multicenter, Double-Blind, Randomized Placebo-and Active-Controlled Dose Range Finding Study of XXX in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control.

A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safetly and Efficacy of the Addition of XXX to Patients With Type 2 Diabetes With Inadequate Glycemic Control on Combined Metformin and Sulfonylurea Therapy.

Supplemental XXX and Low-Glycemic Load Diet in the Management of Type II Diabetes: An Open Label Proof of Concept Study.

Efficacy and Safety of XXX extract in Type II Diabetes Subjects: A Pilot Study.

A 7-arm crossover study to determine the Glycemic Index of White Bread with and without the addition of XXX in capsule and powder form.

Fibromyalgia
A 14 week, randomized, double-blind, placebo-controlled, multi-center study of XXX administered once daily (Q.D.) in subjects with fibromyalgia.

A 14 week Randomized Double-Blind Placebo-Controlled Trial of XXX Twice Daily in Patients with Fibromyalgia.

A 12 week Open-Label Controlled Trial of XXX Twice Daily in Patients with Fibromyalgia.

Supplemental Fish Oil and Low-Glycemic Load Diet in the Management of Fibromyalgia: An Open Label Proof of Concept Study.

Gastroenterology
A Randomized, Double-blind, Placebo-controlled Study of XXX in the Treatment of Irritable Bowel Syndrome with Diarrhea. (IBS-D)

A randomized, double-blind, placebo-controlled, multicenter 2-week pilot study to evaluate the efficacy, safety and tolerability of XXX (xx and xxmg bid) given orally in female patients with Irritable Bowel Syndrome with diarrhea (IBS-D).

A 6-week, randomized, double-blind, placebo-controlled, Multicenter study, to assess the efficacy and safety of oral XXX (xxmg bid) and placebo in female patients with dyspepsia.

A 4-week, Multicenter, double-blind, placebo-controlled, randomized, parallel-group, clinical study to evaluate the efficacy of XXX in relieving the symptoms of female patients with Irritable Bowel Syndrome (IBS), excluding those with predominant diarrhea IBS.

Immune Health / Inflammation
Validation Study of the Immunostimulatory and Antioxidant effects of XXX with and without XXX: A randomized, double-blind, placebo-controlled, parallel-group 3-arm study.

A Randomized, Double-Blind, Placebo Controlled 3-way Crossover Study comparing XXX, XXX, and Placebo.

A XXX Compound (XXX) for the Reduction of Inflammation in an Overweight Population: An open label pilot study.

Obesity
A Proprietary XXX for the Reduction of Oxidative Stress in an Obese Population: A Randomized, Double-Blind, Placebo Controlled Study.

A 1% XXX extract for the improvement of Metabolic Parameters in an Obese Population.
Parallel Studies to Evaluate the Effect of XXX on Body Weight and Satiety in Overweight Women following the XXX Diet compared to a Traditional Calorie Restricted Diet in Two Populations: Non-Diabetic and Diabetic.

XXX for the Reduction of inflammation in an Obese population: A randomized, double-blind, placebo-controlled, dose-finding study.

Short term effect of XXX on satiety and appetite suppression in healthy obese subjects: A 3-way randomized, double-blind, placebo controlled, dose-finding, crossover study

An Eighteen Month Study to Assess the Efficacy, Safety, and Tolerability of XXX in Obese Patients.

Blocking Carbohydrate Absorption and Weight Loss: A Clinical Trial using XXX.

Blocking Carbohydrate Absorption and Weight Loss: A Short-Term Clinical Trial using XXX.

Herbal combination product for the treatment of obesity.

Neurology
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study of XXX in Adult Migraineurs for a Single Migraine Followed by Open-Label Extensions to 26/52 Weeks.

Pharmacokinetics
Relative Pharmacokinetics of XXX in a healthy population: A dose-finding study.

Relative Pharmacokinetics of XXX in a Post-Menopausal female population.

Relative Pharmacokinetics of XXX in a healthy population.

Psychiatry
Effect of XXX on Symptoms of Depression in Individuals with Mild Depression.

Sleep Studies
Efficacy and safety of XXX on Sleep Maintenance Insomnia with a sub-study of the effect of XXX on stable Type II Mellitus: a One Year multi-center, randomized, double-blind, placebo controlled study.

Sports Nutrition
Improvements in Muscle Recovery and DOMS Reduction after Eccentric Exercise with the XXX product: A randomized double-blind placebo, 2-way crossover controlled pilot study.

Women's Health
A Multi-Center, Double-Blind, Placebo Controlled Comparison of Multiple Doses of XXX and XXX, in Combination and Alone, in Relieving Vasomotor Symptoms in Postmenopausal Women.

The effect of XXX on Mammalian Lignan and Estrogen metabolite levels in
Post-Menopausal women: A randomized, single-blind, single-dummy, parallel group, pilot study.

Urology
SELECT Trial (Selenium and Vitamin E for Prevention of Prostate Cancer)